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Cymbalta Generic (duloxetine)
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Cymbalta Generic (duloxetine) Online
Cymbalta Generic (Duloxetine)
Generic Cymbalta (Duzela Capsules) belongs to a group of medicines called Serotonin and Norepinephrine Reuptake Inhibitor (SNRI) which work to increase the amounts of serotonin and norepinephrine, naturally occuring chemicals in the brain that help maintain mental balance and stop the movement of pain signals in the brain.
Generic Cymbalta Capsules are used to treat Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Diabetic Peripheral Neuropathic Pain (DPNP), Fibromyalgia (FM) and Chronic Musculoskeletal Pain. Erectile Wellness Offer Cymbalta Generic 20mg, 30ng, 40mg & 60mg With Discounted Price In USA, UK, Franch.
Duzela capsules are manufactured by Sun Pharmaceutical Industries Ltd. in the strengths of 60 mg. The active ingredient pharmaceutical present in Duzela capsules is Duloxetine Hydrochloride.
We also have in stock Generic Effexor XR (Venlor XR Capsules) which is another medicine used to treat the same indications.
Cymbalta is the brand name for duloxetine, an antidepressant prescribed to treat the symptoms of depression. In addition to depression, doctors can prescribe Cymbalta to treat anxiety that lasts for at least six months, pain from diabetic nerve damage, fibromyalgia, and long-term muscle or bone pain.
Cymbalta is in a class of medications called serotonin-norepinephrine reuptake inhibitors (SNRIs).
It works by increasing the levels of the neurotransmitters serotonin and norepinephrine, which help regulate mood and may block pain signals traveling through the brain.
How should I use this medicine?
Duloxetine (Duzela capsules) is used to treat major depressive disorder and general anxiety disorder. It is an antidepressant in a group of drugs called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). Duloxetine affects chemicals in the brain that may become unbalanced and cause depression.
Generic Cymbalta is also used to treat a chronic pain disorder called fibromyalgia, treat pain caused by nerve damage in people with diabetes (diabetic neuropathy) and to treat chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain.
We supply Duzela by Sun Pharma which is also known as Generic Cymbalta. It contains the active ingredient Duloxetine HCl 60 mg.
How Does Cymbalta Generic Work?
Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressants used for treating depression, anxiety disorder, and pain. Other drugs in this class include milnacipran (Savella), venlafaxine (Effexor), and desvenlafaxine (Pristiq).
Duloxetine affects neurotransmitters, the chemicals that nerves within the brain make and release in order to communicate with one another. Neurotransmitters either travel across the space between nerves and attach to receptors on the surface of nearby nerves or they attach to receptors on the surface of the nerves that produced them, to be taken up by the nerve and released again (a process referred to as re-uptake).
Many experts believe that an imbalance among neurotransmitters is the cause of depression as well as other psychiatric disorders. Serotonin and norepinephrine are two neurotransmitters released by nerves in the brain. Duloxetine works by preventing the reuptake of serotonin and epinephrine by nerves after they have been released.
Since uptake is an important mechanism for removing released neurotransmitters and terminating their actions on adjacent nerves, the reduced uptake caused by duloxetine increases the effect of serotonin and norepinephrine in the brain.
How Do I take Cymbalta Generic?
Take Duzela (Generic Cymbalta, Duloxetine) exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Your doctor may occasionally change your dose to make sure you get the best results.
Try to take Duzela (Generic Cymbalta, Duloxetine) at the same time each day. Do not crush, chew, break, or open a delayed-release capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time.
It may take 4 weeks or longer before your symptoms improve. Keep using Duzela (Generic Cymbalta, Duloxetine) as directed. Do not stop using Duzela (Generic Cymbalta, Duloxetine) without first talking to your doctor. You may have unpleasant side effects if you stop taking Duzela (Generic Cymbalta, Duloxetine) suddenly.
Use of Generic Cymbalta (Duzela Capsules) is contraindicated to treat patients with the following conditions:
Generic Cymbalta Capsules are contraindicated in patients with a hypersensitivity to Duloxetine or any inactive ingredient present in Duzela capsules.
Generic Cymbalta is contraindicated in patients with hepatic impairment.
Generic Cymbalta should not be used in combination with potent CYP1A2 inhibitors
Using Monoamine Oxidase Inhibitors (MAOIs) for treating psychiatric disorders with Generic Cymbalta or within five days of stopping treatment with Generic Cymbalta capsules is contraindicated because of an increased risk of serotonin syndrome. Additionally the use of Duzela capsules within 14 days of stopping an MAOI intended to treat psychiatric disorders is also contraindicated.
Starting treatment with Duzela capsules in a patient who is being treated with MAOIs such as linezolid or intravenous methylene blue is also contraindicated because of an increased risk of serotonin syndrome.
Cymbalta is used for treating depression and generalized anxiety disorder. It is used for managing pain caused by fibromyalgia and diabetic peripheral neuropathy (DPNP). Cymbalta is a serotonin and norepinephrine reuptake inhibitor (SNRI). It works by restoring the balance of certain natural substances in the brain (serotonin and norepinephrine), which helps to improve certain mood problems.
Use Cymbalta as directed by your doctor.
· Take Cymbalta by mouth with or without food. Taking it with food may help to decrease the chance of nausea or stomach upset.
· Swallow Cymbalta whole. Do not break, crush, or chew before swallowing. Do not open the capsule and sprinkle the contents on food or in liquid.
· Take Cymbalta on a regular schedule to get the most benefit from it. Taking Cymbalta at the same time each day will help you remember to take it.
· Continue to take Cymbalta even if you feel well. Do not miss any dose.
· Do not suddenly stop taking Cymbalta without checking with your doctor. Side effects may occur. They may include mental or mood changes, numbness or tingling of the skin, diarrhea, dizziness, confusion, headache, increased sweating, nausea, nightmare, ringing in the ears, seizures, trouble sleeping, unusual tiredness, or vomiting. You will be closely monitored when you start Cymbalta and whenever a change in dose is made.
· If you miss a dose of Cymbalta, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Cymbalta.
Store Cymbalta at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Cymbalta out of the reach of children and away from pets.
Do not use Duzela (Generic Cymbalta, Duloxetine) together with thioridazine (Mellaril), or an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate).
A dangerous drug interaction could occur, leading to serious side effects. You must wait at least 14 days after stopping an MAO inhibitor before you can take this medicine. After you stop taking this medicine, you must wait at least 5 days before you start taking an MAOI. Do not use this medicine if you are allergic to duloxetine, or if you have untreated or uncontrolled glaucoma.
- Take Cymbalta by mouth with or without food. Taking it with food may help to decrease the chance of nausea or stomach upset.
- Swallow Cymbalta whole. Do not break, crush, or chew before swallowing. Do not open the capsule and sprinkle the contents on food or in liquid.
- Take Cymbalta on a regular schedule to get the most benefit from it. Taking Cymbalta at the same time each day will help you remember to take it.
- Continue to take Cymbalta even if you feel well. Do not miss any dose.
- Do not suddenly stop taking Cymbalta without checking with your doctor. Side effects may occur. They may include mental or mood changes, numbness or tingling of the skin, diarrhea, dizziness, confusion, headache, increased sweating, nausea, nightmare, ringing in the ears, seizures, trouble sleeping, unusual tiredness, or vomiting. You will be closely monitored when you start Cymbalta and whenever a change in dose is made.
- If you miss a dose of Cymbalta, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Cymbalta.
Active Ingredient: Duloxetine hydrochloride
Do NOT use Cymbalta if:
· you are allergic to any ingredient in Cymbalta
· you have uncontrolled narrow-angle glaucoma
· you have liver problems or severe kidney problems, or you are having dialysis
· you are taking or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days
· you are taking a quinolone antibiotic (eg, ciprofloxacin), a selective serotonin reuptake inhibitor (SSRI) (eg, fluoxetine, fluvoxamine), an SNRI (eg, venlafaxine), thioridazine, or tryptophan.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Cymbalta. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
· if you are pregnant, planning to become pregnant, or are breast-feeding
· if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
· if you have allergies to medicines, foods, or other substances
· if you or a family member has a history of bipolar disorder (manic-depression), other mental or mood problems, suicidal thoughts or attempts, or alcohol or substance abuse
· if you have a history of seizures, heart problems (eg, heart failure, irregular heartbeat), recent heart attack, high blood pressure, kidney problems, diabetes, stomach or bowel problems (eg, slowed emptying), or increased eye pressure (eg, glaucoma)
· if you are dehydrated, have trouble urinating, have low blood sodium levels, or drink alcohol.
Some medicines may interact with Cymbalta. Tell your health care provider if you are taking any other medicines, especially any of the following:
· 5-HT1 receptor agonists (eg, sumatriptan), linezolid, lithium, MAOIs (eg, phenelzine), quinidine, rasagiline, SNRIs (eg, venlafaxine), SSRIs (eg, fluoxetine, fluvoxamine), St. John's wort, tramadol, or tryptophan because severe side effects, such as a reaction that may include fever, rigid muscles, blood pressure changes, mental changes, confusion, irritability, agitation, delirium, or coma, may occur
· Anticoagulants (eg, warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) because the risk of bleeding, including stomach bleeding, may be increased
· Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood sodium levels may be increased
· Cimetidine, medicines for high blood pressure, or quinolone antibiotics (eg, ciprofloxacin) because they may increase the risk of Cymbalta's side effects
· Certain antiarrhythmics (eg, flecainide, propafenone), phenothiazines (eg, chlorpromazine, thioridazine), or tricyclic antidepressants (eg, amitriptyline) because the risk of their side effects may be increased by Cymbalta.
· This may not be a complete list of all interactions that may occur. Ask your health care provider if Cymbalta may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Important safety information:
· Cymbalta may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Cymbalta with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
· Cymbalta may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
· Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Cymbalta; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
· Several weeks may pass before your symptoms improve. Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
· Do not suddenly stop taking Cymbalta. Some conditions may become worse when the medicine is suddenly stopped or the dose of Cymbalta is decreased. Your dose may need to be slowly lowered to decrease the risk of side effects.
· Children and teenagers who take Cymbalta may be at increased risk for suicidal thoughts or actions. Adults may also be affected. The risk may be greater in patients who have had suicidal thoughts or actions in the past. The risk may also be greater in patients who have had bipolar (manic-depressive) illness, or if their family members have had it. Watch patients who take Cymbalta closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
· Serotonin syndrome is a possibly fatal syndrome that can be caused by Cymbalta. Your risk may be greater if you take Cymbalta with certain other medicines (eg, MAOIs, SSRIs, "triptans"). Symptoms may include agitation; coma; confusion; excessive sweating; fast or irregular heartbeat; fever; hallucinations; nausea, vomiting, or diarrhea; tremor. Contact your doctor at once if you have any of these symptoms.
· Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that can be caused by Cymbalta. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor at once if you have any of these symptoms.
· Diabetes patients - Cymbalta may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
· If your doctor tells you to stop taking Cymbalta, you will need to wait for at least 5 days before beginning to take certain other medicines (eg, MAOIs). Ask your doctor when you should start to take your new medicines after you have stopped taking Cymbalta.
· Lab tests, including blood pressure and liver function, may be performed while you use Cymbalta. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
· Use Cymbalta with caution in the elderly; they may be more sensitive to its effects, especially low blood sodium levels.
· Caution is advised when using Cymbalta in children; they may be more sensitive to its effects, especially increased risk of suicidal thoughts or actions.
· Cymbalta should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.
· Pregnancy and breast-feeding: Cymbalta may cause harm to the fetus if it is used during the last 3 months of pregnancy. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Cymbalta while you are pregnant. Cymbalta is found in breast milk. Do not breastfeed while taking Cymbalta.
All medicines may cause side effects, but many people have no, or minor, side effects.
· Check with your doctor if any of these most common side effects persist or become bothersome:
· Constipation; decreased sexual desire or ability; diarrhea; dizziness; drowsiness; dry mouth; headache; increased sweating; loss of appetite; nausea; sore throat; tiredness; trouble sleeping; vomiting; weakness.
· Seek medical attention right away if any of these severe side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bizarre behavior; bloody or black, tarry stools; blurred vision; confusion; dark urine; decreased concentration; decreased coordination; excessive sweating; fainting; fast or irregular heartbeat; fever or chills; hallucinations; memory loss; new or worsening aggressiveness, agitation, anxiety, hostility, impulsiveness, irritability, panic attacks, restlessness, or inability to sit still; pale stools; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; severe or persistent dizziness or headache; severe or persistent nausea, vomiting, or diarrhea; severe or persistent tiredness or weakness; severe or persistent trouble sleeping; stiff muscles; stomach pain; suicidal thoughts or attempts; tremor; trouble urinating or change in the amount of urine produced; unusual bruising or bleeding; unusual or severe mental or mood changes; unusual weakness; vomit that looks like coffee grounds; worsening of depression; yellowing of the skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.