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Alli Generic (Orlistat)
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Alli Generic (Orlistat)
Alli is a 60-milligram, over-the-counter version of orlistat (Xenical), a 120-milligram prescription drug. Both Alli and Xenical are meant to be used as part of a weight-loss plan that includes a low-calorie, low-fat diet and regular physical activity.
Alli is approved for use in adults 18 and older who have a body mass index (BMI) of 25 or more. Xenical is approved for use in adults with a BMI of 30 or more (obese), and those with a BMI of 27 to 29 (overweight) who have other health risk factors such as high blood pressure or diabetes.
alli is an FDA approved weight loss supplement that helps block about 25 percent of the fat you eat from being absorbed. Acts as an effective weight loss product and diet pill for both women and men
For every 5 pounds you lose through diet and exercise, alli can help you lose 2 to 3 more.
alli weight loss supplement works in the digestive tract and is minimally absorbed into the bloodstream, so there are no direct effects on the cardiovascular or central nervous system.
alli capsules are a weight loss pill for overweight adults, 18 years and older, when used along with a reduced calorie and low fat diet.
How should I use this medicine?
If you are taking the over-the-counter product to self-treat, read all directions on the product package before taking this medication.
If your doctor has prescribed this medication, read the Patient Information Leaflet if available from your pharmacist before you start taking orlistat and each time you get a refill. Take this medication as directed by your doctor, by mouth with liquid sometime during each meal that contains fat or within 1 hour after the meal, usually 3 times daily.
If you miss a meal or your meal contains no fat, skip that dose of the medication. To decrease the chance of unpleasant side effects, it is very important that no more than 30% of the calories in your diet come from fat. Your daily intake of fat, protein, and carbohydrates should be evenly spread over 3 main meals.
Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Because this drug can interfere with the absorption of certain vitamins (fat-soluble vitamins including A, D, E, K), a daily multivitamin supplement containing these nutrients is recommended. Take the multivitamin at least 2 hours before or 2 hours after taking orlistat (such as at bedtime).
If you take cyclosporine, take it at least 3 hours before or after orlistat to make sure the full dose of cyclosporine is absorbed into your bloodstream. If you take levothyroxine, take it at least 4 hours before or after orlistat. You should see some weight loss within 2 weeks after you start orlistat. Tell your doctor if your condition does not improve or if it worsens.
How Does Alli Work?
Orlistat (the active ingredient in Alli) promotes weight loss by decreasing the amount of dietary fat absorbed in your intestines.
Lipase, an enzyme found in the digestive tract, helps break down dietary fat into smaller components, so it can be used or stored for energy. Orlistat inhibits the work of lipase. When you take the drug with a meal, about 25 percent of the fat you consume isn't broken down and is eliminated through bowel movements.
How do I take Alli?
One 60-milligram Alli pill is taken within an hour of a fat-containing meal up to three times a day. Daily fat intake should be distributed over the three main meals and should be no more than 30 percent of total calories. The manufacturer recommends a fat intake of about 15 grams a meal.
If you eat a meal that contains no fat, then you don't need a dose of Alli. If you take Alli with a high-fat meal, you will likely experience more-severe gastrointestinal side effects.
Alli can reduce the absorption of fat-soluble nutrients, including beta carotene and vitamins A, D, E and K. Take a multivitamin at bedtime and at least two hours after your last dose of Alli.
Alli is used for managing obesity in overweight adults. It is also used to reduce the risk of weight regain after previous weight loss. It is used along with a reduced-calorie, low-fat diet. Alli is a gastrointestinal lipase inhibitor. It works by blocking the digestion of fats from the diet.
Use Alli as directed by your doctor.
· Take Alli by mouth with each meal containing fat. Do not take more than 3 capsules daily.
· If a meal is missed or contains no fat, do not take a dose of Alli.
· Alli may decrease your absorption of vitamins. Take a multivitamin once a day at bedtime.
· If you also take a thyroid hormone (eg, levothyroxine), do not take it within 4 hours before or after Alli. Check with your doctor if you have questions.
· If you also take cyclosporine, do not take it within 2 hours before or after Alli. Check with your doctor before you take Alli with cyclosporine.
· If you miss a dose of Alli, take it as soon as you remember. Continue taking it as directed by your doctor.
Ask your health care provider any question you may have about how to use Alli.
The recommended dose of alli (orlistat 60 mg) for overweight adults 18 years and older is 1 60-mg capsule with each meal containing fat.
- do not exceed 3 capsules daily
- Use with a reduced-calorie, low-fat diet until you reach your weight loss goal.
Most weight loss occurs within the first 6 months. If you stop using alli (orlistat 60 mg), continue with a diet and exercise program. If you start to regain weight after you stop taking alli (orlistat 60 mg), you may need to start taking alli (orlistat 60 mg) again along with your diet and exercise program.
Take a multivitamin once a day, at bedtime, when using alli (orlistat 60 mg) capsules.
Where should I keep my medicine?
Store Alli between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Alli out of the reach of children and away from pets.
In addition to side effects, Alli may be harmful to your liver. In 2010, the FDA updated its requirements for the labeling of orlistat products to include a safety information about a few cases of severe liver injury linked to the weight-loss pill. If you have a pre-existing liver condition or experience jaundice, severe itching, or dark urine, see your doctor.
As with all medications, take caution to purchase Alli from a reputable vendor and check the package closely before taking a pill. In 2014, product tampering was reported and resulted in a voluntary recall of the diet pills. Alli came back on the market with an updated package that makes it easier to see if the bottle has been opened.
Active Ingredient: Orlistat.
Alli (Orlistat) is the weight loss product that can help losing about 50% more weight than with just dieting alone.
Do not use Alli if:
· you are allergic to any ingredient in Alli
· you are not overweight
· you have gallbladder problems, bile flow problems (eg, cholestasis), or problems absorbing food (malabsorption).
Contact your doctor or health care provider if any of these apply to you.
Some medical conditions may interact with Alli. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
· if you are pregnant, planning to become pregnant, or are breast-feeding
· if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
· if you have allergies to medicines, foods, or other substances
· if you have an eating disorder (eg, anorexia, bulimia)
· if you have a history of gallbladder, liver, pancreas, or thyroid problems; diabetes; or kidney stones
· if you take medicine for diabetes or thyroid problems, or if you take any other medicines for weight loss
· if you have received an organ transplant or if you take cyclosporine.
Some medicines may interact with Alli. Tell your health care provider if you are taking any other medicines, especially any of the following:
· Anticoagulants (eg, warfarin) because the risk of bleeding may be increased by Alli
· Amiodarone, cyclosporine, or thyroid hormones (eg, levothyroxine) because their effectiveness may be decreased by Alli.
This may not be a complete list of all interactions that may occur. Ask your health care provider if Alli may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Important safety information:
· Do NOT take more than the recommended dose without checking with your doctor. Taking more than the recommended dose may not help you lose more weight. It may increase your risk of side effects.
· Proper diet and exercise are important in order to lose weight and keep it off. Follow the diet and exercise program given to you by your health care provider.
· Alli may cause changes in your bowel or stool (eg, gas with oily spotting, loose stools, more frequent stools). Eating a low-fat diet may help lessen these side effects.
· Tell your doctor or dentist that you take Alli before you receive any medical or dental care, emergency care, or surgery.
· Diabetes patients - Alli may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
· Some patients taking Alli have developed severe liver problems. It is not known if liver problems may be caused by Alli. Contact your doctor right away if you experience yellowing of the skin or eyes, dark urine, pale stools, unusual weakness, loss of appetite, or severe or persistent nausea.
· Alli should not be used in children younger than 18 years old; safety and effectiveness in these children have not been confirmed.
· Pregnancy and breast-feeding: Do not take Alli if you are pregnant. If you become pregnant, contact your doctor. It is not known if Alli is found in breast milk. Do not breastfeed while taking Alli.
Check with your doctor if any of these most common side effects persist or become bothersome:
Breast tenderness; bleeding or spotting between menstrual periods; nausea; stomach cramps or bloating; vomiting; weight gain.
Seek medical attention right away if any of these severe side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); breast lump or discharge; calf or leg pain, swelling, or tenderness; change in the amount of urine produced; chest pain or heaviness; confusion; coughing of blood; fainting; irregular heartbeat; left-sided jaw, neck, shoulder, or arm pain; mental or mood changes (eg, depression); migraines; missed menstrual period; numbness of an arm or leg;
one-sided weakness; persistent, severe, or recurring
headache or dizziness; persistent vaginal spotting; severe or persistent
trouble sleeping; severe stomach pain or tenderness; shortness of breath;
slurred speech; sudden severe vomiting; swelling of the fingers, hands, legs,
or ankles; symptoms of liver problems (eg, yellowing of the skin or eyes,
fever, dark urine, pale stools, loss of appetite); unusual or severe vaginal
bleeding; unusual tiredness or weakness; vaginal irritation or discharge;
vision changes (eg, sudden vision loss, double vision).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.