Acivir Cream ® (Aciclovir)

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Acivir Cream ® (Aciclovir) 5gm CHECK PRICES

Product of India

Manufactured by: Cipla Limited
Active Ingredient: Acyclovir

Acivir Cream ® (Aciclovir)

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Acivir Cream ® (Aciclovir) Overview

Acivir Cream ® (Aciclovir)

Acivir 0.05% Cream is an antiviral agent which is used in the treatment of infections caused by herpes virus such as chickenpox and herpes zoster.

Aciclovir is indicated for the treatment of HSV and VZV infections, including:

·         Genital herpex simplex

·         Herpes simplex labialis

·         Herpes zoster (shingles)

·         Acute chickenpox in immunocompromised patients

·         Herpes simplex encephalitis

·         Acute mucocutaneous HSV infections in immunocompromised patients

·         Herpes simplex keratitis (ocular herpes)

·         Herpes simplex blepharitis

·         Bell's Palsy

Aciclovir is an antiviral. It works by stopping viral replication. However, Aciclovir does not eliminate the virus, is not a cure, and does not prevent transmission to others.

How should I use this medicine?

Take Acyclovir exactly as directed by your doctor. Do not take more or less than instructed. Do not skip any doses. Continue to take it even when you feel better. You must complete the entire course. If you dont, the infection will not clear completely.

You may take Acyclovir with or without food. If you experience stomach discomfort, you may take Aciclovir after food. Drink plenty of water while being treated with Acyclovir.

How Does Acivir Cream Work?

The active ingredient in Unisom is an antihistamine. Another antihistamine that may sound familiar is diphenhydramine, the active ingredient in medications like Benadryl.

When you take Unisom, the medication blocks the production of histamine and acetylcholine in the body. When these compounds are reduced, a person will start to feel sleepier.

If you are only having trouble sleeping while pregnant, your doctor might recommend Benadryl. Unisom is likely to be recommended for consistent nausea and vomiting during pregnancy.

How to take Acivir Cream?

When you’re expecting, you and your baby share more than your belly. Everything you eat, take, and sometimes even put on your skin can be circulated through your baby, too. That’s why things like sushi, deli meats, aspirin, and skin care products with retinoids are off-limits.

From an FDA perspective, Unisom has been generally considered safe for pregnant women.

But, talk to your doctor before taking any medications. Together, you can discuss the medication’s potential effects on your baby and ensure that it won’t interact with other medications you are taking.

Think about the risks and benefits before taking Unisom. If your sleep is greatly affected to the point where you are having difficulty functioning during the day, talk to your doctor.

Dosage:

Acivir Cream should be applied 5 times per day for 4 days. Therapy should be initiated as early as possible following onset of signs and symptoms (i.e. during the Prodrome or when lesions appear). For adolescents 12 years of age and older, the dosage is the same as in adults.

Overdosage

No untoward effects would be expected if the entire contents of a 10 g tube of aciclovir cream containing 500 mg of aciclovir were ingested orally. However the accidental, repeated overdose of oral aciclovir, over several days has resulted in gastrointestinal effects (nausea and vomiting) and neurological effects (headache and confusion). Aciclovir is dialysable by haemodialysis.

Where should I keep my medicine?

Store Unisom at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store in the original package or container away from heat, moisture, and light. Do not store in the bathroom. Keep Unisom out of the reach of children and away from pets.

Overdosage

No untoward effects would be expected if the entire contents of a 10 g tube of aciclovir cream containing 500 mg of aciclovir were ingested orally. However the accidental, repeated overdose of oral aciclovir, over several days has resulted in gastrointestinal effects (nausea and vomiting) and neurological effects (headache and confusion). Aciclovir is dialysable by haemodialysis.

Where should I keep my medicine?

Store Unisom at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store in the original package or container away from heat, moisture, and light. Do not store in the bathroom. Keep Unisom out of the reach of children and away from pets.

Contraindications:

Acivir Cream is contraindicated in patients with a known hypersensitivity to aciclovir, valaciclovir, or any component of the formulation.

Warnings and Precautions:

Acivir Cream is intended for cutaneous use only and should not be used in the eyes or inside the mouth, nose or vagina as it may cause irritation. ACIVIR Cream should only be used on herpes labialis on the affected external aspects of the lips and face.

Aciclovir cream has a potential for irritation and contact sensitization. The effect of aciclovir cream has not been established in immunocompromised patients.

Pregnancy

The birth defects described amongst subjects exposed to aciclovir have not shown any uniqueness or consistent pattern to suggest a common cause. The use of aciclovir cream should be considered only when the potential benefits outweigh the possibility of unknown risks.

Lactation

It is not known whether topically applied aciclovir is excreted in breast milk. Systemic exposure following topical administration is minimal.

After oral administration of aciclovir, aciclovir concentrations have been documented in breast milk in 2 women and ranged from 0.6 to 4.1 times the corresponding plasma levels. These concentrations would potentially expose the nursing infant to a dose of aciclovir up to 0.3 mg/kg/day.

Nursing mothers who have active herpetic lesions near or on the breast should avoid nursing.

Paediatric Use

Safety and effectiveness in paediatric patients less than 12 years of age have not been established.

Geriatric Use

Clinical studies of aciclovir cream did not include sufficient numbers of subjects aged 65 years and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. Systemic absorption of aciclovir after topical administration is minimal.

Active Ingredient: Doxylamine.

Safety Information

Do not use Acivir Cream if:

·         you are allergic to any ingredient in Aciclovir or to valacyclovir

·         Contact your doctor or health care provider right away if any of these apply to you.

·         Some medical conditions may interact with Aciclovir. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

·         if you are pregnant, planning to become pregnant, or are breast-feeding

·         if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

·         if you have allergies to medicines, foods, or other substances

·         if you have kidney problems or a weakened immune system.

Some medicines may interact with Aciclovir. Tell your health care provider if you are taking any other medicine, especially any of the following:

·         Medicines that may harm the kidney (eg, aminoglycoside antibiotics [eg, gentamicin], amphotericin B, cyclosporine, nonsteroidal anti-inflammatory drugs [NSAIDs] [eg, ibuprofen], tacrolimus, vancomycin) because the risk of kidney side effects may be increased. Ask your doctor if you are unsure if any of your medicines might harm the kidney.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Aciclovir may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

·         Aciclovir may cause drowsiness, dizziness, vision changes, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Aciclovir with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

·         Aciclovir may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit down or stand up slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

·         Aciclovir may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Aciclovir. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.

·         Aciclovir is not a cure for genital herpes and will not prevent the virus from spreading. Avoid sexual intercourse when sores are present to prevent infecting your partner. You can also be contagious and spread the herpes virus but not have any signs or symptoms at all. This is called asymptomatic viral shedding.

·         Lab tests, including kidney function and serum urea nitrogen (BUN), may be performed while you use Aciclovir. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

·         Use Aciclovir with caution in the elderly; they may be more sensitive to its effects, especially confusion, drowsiness, or hallucinations.

·         Aciclovir is not recommended for use in children younger than 2 years old as safety and effectiveness for children have not been confirmed.

·         Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Aciclovir while you are pregnant. Aciclovir is found in breast milk. If you are or will be breast-feeding while you use Aciclovir, check with your doctor. Discuss any possible risks to your baby.

Side Effects

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Diarrhea; general body discomfort; headache; nausea/vomiting.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); aggressive behavior; blood in the urine; confusion; decreased consciousness; decreased urination; hallucinations; lower back pain; mental or mood changes; red, swollen, blistered, or peeling skin; seizures; unusual bruising or bleeding.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.


The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.