Artesunate Injection

Buy Artesunate Injection Online

Artesunate Injection

Artesunate is an antimalarial agent. Artesunate Injection is a water-soluble hemisuccinate derivative of artemisinin. It is unstable in a neutral solution and the injectable formulation must be prepared immediately before use in 5% (w/v) sodium bicarbonate solution to produce the salt sodium artesunate.

After parenteral administration, it is rapidly hydrolyzed to the active metabolite dihydroartemisinin. The oral formulation is probably hydrolyzed completely before entering the systemic circulation. Artesunate has been reported to clear fever in patients with severe falciparum malaria 16-25 hours after parenteral administration.

What is used for Artesunate injection?

Artesunate injection is an alternative therapy for the treatment of severe malaria, including cerebral malaria.

How Does Works Artesunate injection?

Artesunate belongs to a class of medications called anti-malarial. It acts by producing free radicals which kill the malarial parasite (plasmodium).

How to use Artesunate injection?

Always take artesunate tablets exactly as your doctor or health care provider has told you. Artesunate injection tablets are usually taken in combination with another medicine to treat malaria. Artemisinin-based combination therapy (act) in combination therapy in adults and children, artesunate should be given at 4 mg/kg body weight once daily for three days (range 2-10 mg/kg, 200 mg per day in adults). Artesunate dosing scheme in combination therapy (treatment duration 3 days) age no of tablets per day (dose) 1-6 years 1 tablet once daily (50 mg/day) 7-13 years 2 tablets once daily (100 mg/day) older than13 years 4 tablets once daily (200 mg/day)

Artesunat injection Dosage?

Missed Dose

Contact your doctor immediately if you miss a scheduled dose of Artesunate injection 60mg and 120mg injections.

Overdose

Contact your family doctor immediately if an overdose on this medicine is suspected.

Is artesunate FDA approved?

Currently, only one non-oral drug is FDA-approved and available to treat severe malaria cases in the United States. On June 21, 2007, the Food and Drug Administration (FDA) approved investigational new drug (IND) protocol # 76,725, entitled Intravenous Artesunate for Treatment of Severe Malaria in the United States.

What is the best injection for malaria?

Several salts of quinine have been formulated for parenteral use, but dihydrochloride is the most widely used. The peak concentrations after intramuscular quinine in severe malaria are similar to those after intravenous infusion.